VIII Reunión de la Sociedad de Ginecología Oncológica de Castilla y León VII Reunión y I Online SoGOCyL 2021 Jornadas SoGOCyL 2020 Conclusiones de las Jornadas SoGOCyL 2019
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VIII Reunión de la Sociedad de Ginecología Oncológica de Castilla y León

Este 2023 nos complace anunciar que la VIII Reunión de la SoGOCyL tendrá lugar los días 16 y 17 de noviembre en Valladolid.

VII Reunión y I Online SoGOCyL 2021

En 2021 la Reunión de la Sociedad de Ginecología Oncológica de Castilla y León se celebrará online los días 2 y 3 de junio.

Jornadas SoGOCyL 2020

La VII Reunión de la Sociedad de Ginecología Oncológica de Castilla y León tendrá lugar los días 7 y 8 de mayo de 2020 en León.

Conclusiones de las Jornadas SoGOCyL 2019

Éstas son las conclusiones que los profesionales extraemos de la VI Reunión de la Sociedad de Ginecología Oncológica y Patología Mamaria de Castilla y León.

Inicio Fertility considerations in the management of gynecologic malignancies

Fertility considerations in the management of gynecologic malignancies

Miércoles, 19 de Enero de 2011 23:36

Fertility considerations in the management of gynecologic malignancies

Review

Nicole Noyes (a), Jaime M. Knopman (a), Kara Long (b), Jaclyn M. Coletta (c), Nadeem R. Abu-Rustum (b)

(a) Division of Reproductive Endocrinology, New York University School of Medicine, New York, NY, USA. (b) Division of Gynecologic Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. (c) Division of Maternal Fetal Medicine, Columbia University Medical Center, New York, NY, USA

Keywords: Fertility preservation, Oocyte cryopreservation, Cancer, Parenthood, Quality-of-life

Goals. Gynecologic cancers represent a significant proportion of malignancies affecting women. Historically, cancer treatment focused primarily on eradicating disease, irrespective of the impact on fertility. The implementation of early detection protocols and advanced treatment regimens has resulted in improved prognosis for gynecologic cancer patients. With this improvement, more attention is now paid to quality-oflife issues. Fertility preservation (FP) has become an integral component in the selection and execution of gynecological cancer management. In this report we address gynecologic malignancies as they relate to future fertility potential.

Methods. We review reproductive principles such as ovarian reserve, uterine function, cervical competence, and early obstetrical management, as well as available FP methods. In addition, we discuss the potential damage that cancer and cancer treatments can impart on the female reproductive system. We offer general recommendations regarding baseline screening tests useful in assessing the feasibility of FP. Lastly, cancer-specific FP methods are presented.

Results. Oocyte quantity and quality naturally decline with advancing age. In most patients, the slope of decline steepens significantly after the age of 35. Reliable ovarian reserve measures exist and should be utilized to assess and triage potential candidates for FP. Advancements in FP, particularly in oocyte cryopreservation (OC), have improved the success rates associated with the techniques available to cancer patients. Currently, where successfully available, OC appears to be the preferred method for single women diagnosed with a gynecologic malignancy as it affords reproductive autonomy, whereas embryo cryopreservation using a donor gamete remains an alternative.

Conclusions. In gynecologic oncology, effective treatments to achieve cancer survival can compromise the ability to subsequently conceive and/or carry a child. Therefore, as the field of oncofertility continues to expand, a discussion regarding FP should be initiated when tailoring a cancer treatment protocol.

© 2010 Elsevier Inc. All rights reserved.

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